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Ursodeoxycholic acid

Ursodeoxycholic acid

Product Details:

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Product Description

Name:  Ursodeoxycholic acid

Synonyms:  3,7-Dihydroxycholan-24-oic acid; 3alpha,7beta-Dihydroxy-6beta-cholan-24-oic acid; Ursodiol

Molecular Formula:  C24H40O4

Molecular Weight:  392.58

CAS Number:  128-13-2

EINECS:  204-879-3

 

Ursodeoxycholic acid can be chemically synthesized. Ursodeoxycholic acid reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones in patients who want an alternative to surgery. The drug is very expensive, however, and if the patient stops taking it, the gallstones tend to recur if the condition that gave rise to their formation does not change. For these reasons, Ursodeoxycholic acid has not supplanted surgical treatment by cholecystectomy.

UDCA is used to treat primary biliary cirrhosis. In children, its use is not licensed, as its safety and effectiveness are not established. Ursodeoxycholic acid reduces elevated liver enzyme levels by facilitating bile flow through the liver and protecting liver cells.

 

Specification

Test Items

Specifications

Appearance

White or off-white crystalline powder

Identification

Accord with the test

Assay

98.5-101.5%

Particle size

98% pass 40 mesh

Specific rotation

+57o to +62o

Melting point

200-205o

Loss on drying

1.0% Max

Residue on ignition

0.2% Max

Heavy metals

10ppm Max

 

Packing: 25KG net fiber drum.

Storage:   Stored in a dry and cool place, keep away from strong light and heat.

Shelf life:  Two years when stored properly in a well-closed container.

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