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CAS number [9003-39-8]
Polyvinylpolypyrrolidone (PVPP, crospovidone) is a highly cross-linked modification of PVP.
The monomer is extremely toxic to aquatic life. However, the polymer PVP was used as a blood plasma expander for trauma victims after the first half of the 20th century.[clarification needed]
It is used as a binder in many pharmaceutical tablets; it simply passes through the body when taken orally. However, autopsies have found that crospovidone does contribute to pulmonary vascular injury in substance abusers who have injected pharmaceutical tablets intended for oral consumption. The long-term effects of crospovidone within the lung are unknown. PVP added to Iodine forms a complex called (Povidone-iodine) that possesses disinfectant properties. This complex is used in various products like solutions, ointment, pessaries, liquid soaps and surgical scrubs. It is known for instance under the trade name Betadine.
PVP binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers.


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