Name:Menadione
Synonyms:2-Methyl-1,4-naphthoquinone; Vitamin K2(0); Vitamin K3; 2-Methyl-1,4-dihydronaphthalene-1,4-dione
Molecular Formula:C11H8O2
Molecular Weight:172.18
CAS Registry Number:58-27-5
EINECS:200-372-6
Despite the fact that it can serve as a precursor to various types of vitamin K, menadione is generally not used as a nutritional supplement. Large doses of menadione have been reported to cause adverse outcomes including hemolytic anemia due to G6PD deficiency, neonatal brain or liver damage, or neonatal death in some cases. Moreover, menadione supplements have been banned by the U.S. Food and Drug Administration (FDA) because of their high toxicity. Menadione has been used experimentally as a chemotherapic agent for cancer, ca 1945, but has lost ground to much safer, human form, vitamin K2 vitamers. Low level menadione is still used as an inexpensive micronutrient for livestock in many countries.
Lately, menadione has been mentioned again as a treatment for cancer in conjunction with vitamin C (See "The end of cancer" by April Kirkendoll) but modern researchers and trials are investigating nontoxic K2 vitamers such as menaquinone-4 in conjunction with more comprehensive regimens.
Specifications:
Product name
Vitamin K3
Item
Standard
Assay (as Menadione Sodium Bisulphite)
96 % Min.
Menadione
51 % Min.
Moisture
13.0% Max.
Heavy Metals
0.002% Max.
Arsenic
0.0005% Max.
Appearance
White or Gray Yellow Crystalline Powder
Net Weight: 25kg
Storage: Against light,moisture and high temperature.
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