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1077-28-7 Alpha Lipoic Acid

1077-28-7 Alpha Lipoic Acid

Product Details:


Product Description


Name: alpha  Lipoic acid

Synonyms:  (R)-(+)-1,2-Dithiolane-3-pentanoic acid

Molecular Formula:  C8H14O2S2

Molecular Weight:  206.33

CAS Number:  1200-22-2


 Alpha Lipoic acid is a disulfide compound found naturally in mitochondria as the coenzyme for pyruvate dehydrogenase and a-ketoglutarate dehydrogenase. Alpha lipoic acid (ALA) is a unique, vitamin-like antioxidant which exists in two forms, R-alpha-lipoic acid and S-alpha-lipoic acid. These two forms contain the same number and composition of atoms but have different arrangements of the atoms in their respective molecules. Natural lipoic acid is R Alpha lipoic acid. Synthetic lipoic acid contains a 50/50 mixture of the two forms. Studies with the mixture demonstrated beneficial effects in treating a number of diseases and conditions. More recent research has shown that the R Alpha Lipoic acid alone is far more effective than S Alpha Lipoic acid or the mixture. Recently, pure R Alpha Lipoic acid has become available as a nutritional supplement.

R Alpha Lipoic acid is regarded by many as the supreme antioxidant. R-Lipoic acid is unique in that it functions as both a fat and water-soluble antioxidant that can easily cross cell membranes. Thus, it can confer free radical protection to both interior and exterior cellular structures. In summary, R Lipoic Acid acts as a potent anti-oxidant on its own, serves to regenerate other anti-oxidants like vitamin E, Vitamin C and glutathione, and increases the production of glutathione. As a nutritional supplement, doses of 50 to 100 mg. per day are generally recommended. As a Therapeutic agent, higher doses may be used.



Product name

R-(+)-alpha-Lipoic acid




A pale yellow crystal with a characteristic odor,tasteless


Meets the requirements

Melting point



0.388% Max.

Specific optical Rotation(C=1,Ethanol)

+100 to +120°

Loss on drying

0.5% Max.

Residue on ignition

0.1% Max.

Heavy metals

10ppm Max.

Total Microbial Count

1,000 per/g Max.

Moulds and Yeasts

100 per/g Max.

Escherichia coli





99.00% Min.( by HPLC)


Package:  In 5Kg or 25KG net each, cardboard drums with inner plastic bags.

Storage:   Stored in a dry and cool place at temperature below 30°C, keep away from strong light and heat.

Shelf life: Two years when stored properly in a well-closed container.

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